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Research Highlights

Research Highlights /

Research Highlights

Professor AHN Kwangseog's Team Discovers Breakdown Enzyme for HIV

Sep 29, 2020

Researcher RYOO Jeongmin
Researcher RYOO Jeongmin

Professor AHN Kwangseog and researcher RYOO Jeongmin (Dept. of Biological Sciences) have discovered an enzyme which breaks down HIV, the virus which causes AIDS, and presented a possibility for a new type of AIDS vaccine. This team found that ‘SAMHD-1’ protein, which consists of 626 amino acids, decomposes the RNA of HIV. They also found that when the concentration of base in a given cell is low, the ‘SAMHD-1’ becomes active and breaks down HIV RNA. Professor Ahn said that “this discovery will provide an important basis for future vaccine developments,” as many anti-HIV medicines rely on keeping the concentration of base in a low state.

Summary by LEE Hee Un, SNU English Editor, gurume0221@snu.ac.kr